Basic information of LRP2 :
| Official Symbol of Gene | LRP2 |
| Species | Homo sapiens |
| Entrez Gene ID | 4036 |
| Official Full Name | LDL receptor related protein 2 |
| Also known as | DBS; GP330; LRP-2 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000081479 MIM:600073; AllianceGenome:HGNC:6694 |
| Map Location | 2q31.1 |
| Variation Type | SNP |
| refSNP ID | rs12988804 |
Sample information of multiple sclerosis:
| Detected Sample | Blood |
| Sample Detail | N/A |
| Detected Method | TaqMan |
| Disease | MS |
| Disease subtype | PPMS |
| Population | Danish |
| Sample Size | 60 PPMS |
Literature information of multiple sclerosis :
| Pubmed ID | 34678704 |
| Year | 2021 |
| Title | Smoking, cardiovascular risk factors and LRP2 gene variation: Associations with disease severity, cognitive function and brain structure in primary progressive multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | positive |
| Result | The LRP2 risk allele was associated with decreased performance on the California Verbal Learning Test 2 after correction (CC vs. CT+TT 95% CI -14.2--3.4, p = 0.0018). |
| Mechanism/Pathway | N/A |
