Basic information of C3 :
| Official Symbol of Gene | C3 |
| Species | Homo sapiens |
| Entrez Gene ID | 718 |
| Official Full Name | complement C3 |
| Also known as | ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000125730 MIM:120700; AllianceGenome:HGNC:1318 |
| Map Location | 19p13.3 |
| Variation Type | SNP |
| refSNP ID | rs2230199 |
Sample information of multiple sclerosis:
| Detected Sample | Blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | 161 relapse-onset MS |
Literature information of multiple sclerosis :
| Pubmed ID | 29485352 |
| Year | 2019 |
| Title | Convergent effects of a functional C3 variant on brain atrophy, demyelination, and cognitive impairment in multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | positive |
| Result | C3-rs2230199 affects white and GM damage as well as cognitive impairment in MS patients. |
| Mechanism/Pathway | N/A |
