Details

Home Details


Basic information of ACE :

Official Symbol of Gene ACE
Species Homo sapiens
Entrez Gene ID 1636
Official Full Name angiotensin I converting enzyme
Also known as DCP; ACE1; DCP1; CD143
Gene Type protein coding
dbXrefs Ensembl:ENSG00000159640 MIM:106180; AllianceGenome:HGNC:2707
Map Location 17q23.3
Variation Type ACE homozygotes, II
refSNP ID N/A

Sample information of multiple sclerosis:

Detected Sample Blood
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype N/A
Population Serbian
Sample Size 470 MS patients and 478 controls

Literature information of multiple sclerosis :

Pubmed ID 27000216
Year 2016
Title Renin-angiotensin system gene polymorphisms as risk factors for multiple sclerosis

Results of multiple sclerosis :

Risk Type Disease risk
Main Result positive
Result Both ACE homozygotes, II and DD, were significantly overrepresented in MS patients, compared to controls (χ(2) test p=0.03).
Mechanism/Pathway N/A