Basic information of PTPRC :
| Official Symbol of Gene | PTPRC |
| Species | Homo sapiens |
| Entrez Gene ID | 5788 |
| Official Full Name | protein tyrosine phosphatase receptor type C |
| Also known as | LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; IMD105 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000081237 MIM:151460; AllianceGenome:HGNC:9666 |
| Map Location | 1q31.3-q32.1 |
| Variation Type | C77G |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | Blood |
| Sample Detail | N/A |
| Detected Method | subsequent dot-blot analysi |
| Disease | MS |
| Disease subtype | N/A |
| Population | Sardinian |
| Sample Size | 241 patients and 217 healthy sibs |
Literature information of multiple sclerosis :
| Pubmed ID | 15372250 |
| Year | 2004 |
| Title | PTPRC (CD45) C77G mutation does not contribute to multiple sclerosis susceptibility in Sardinian patients |
Results of multiple sclerosis :
| Risk Type | N/A |
| Main Result | negative |
| Result | We concluded that, despite the presence of CD45 G77 polymorphism in a few patients who did not carry the HLADR- DQ MS-predisposing molecules, CD45 did not contribute to development of the disease in Sardinian MS. |
| Mechanism/Pathway | N/A |
