Basic information of FCGR3B :

Official Symbol of Gene	FCGR3B
Species	Homo sapiens
Entrez Gene ID	2215
Official Full Name	Fc gamma receptor IIIb
Also known as	CD16; FCG3; CD16A; CD16b; FCGR3; CD16-I; FCGR3A; FCR-10; FCRIII; FCRIIIb
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000162747 MIM:610665; AllianceGenome:HGNC:3620
Map Location	1q23.3
Variation Type	allele
refSNP ID	N/A

Sample information of multiple sclerosis:

Detected Sample	Blood
Sample Detail	N/A
Detected Method	PCR
Disease	MS
Disease subtype	N/A
Population	N/A
Sample Size	136 MS patients and 96 matched controls

Literature information of multiple sclerosis :

Pubmed ID	10371522
Year	1999
Title	Immunoglobulin G Fc-receptor (FcgammaR) IIA and IIIB polymorphisms related to disability in MS

Results of multiple sclerosis :

Risk Type	N/A
Main Result	negative
Result	The allele frequencies of the FcgammaRIIA and FcgammaRIIIB did not differ significantly between the MS patients and the controls.
Mechanism/Pathway	FcgammaRIIIB NA1/NA1 and FcgammaRIIA H/H bind more efficient IgG1/IgG3 and IgG2 subclasses, respectively, than FcgammaRIIIB NA2/NA2 and FcgammaRIIA R/R. A more effective processing of circulating immune complexes may be one mechanism for better clinical outcome in MS.