Basic information of IL7R :
| Official Symbol of Gene | IL7R |
| Species | Homo sapiens |
| Entrez Gene ID | 3575 |
| Official Full Name | interleukin 7 receptor |
| Also known as | ILRA; CD127; IL7RA; CDW127; IMD104; sIL-7R; lnc-IL7R; IL7Ralpha; IL-7Ralpha; IL-7R-alpha |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000168685 MIM:146661; AllianceGenome:HGNC:6024 |
| Map Location | 5p13.2 |
| Variation Type | SNP |
| refSNP ID | rs3194051 |
Sample information of multiple sclerosis:
| Detected Sample | Blood |
| Sample Detail | N/A |
| Detected Method | Sequenom MassARRAY system |
| Disease | MS |
| Disease subtype | N/A |
| Population | Arab Jordanian |
| Sample Size | 218 Arab Jordanian MS patients |
Literature information of multiple sclerosis :
| Pubmed ID | 32111053 |
| Year | 2020 |
| Title | Association of Multiple Sclerosis Phenotypes with Single Nucleotide Polymorphisms of IL7R, LAG3, and CD40 Genes in a Jordanian Population: A Genotype-Phenotype Study |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | positive |
| Result | In this study, MS patients who had vitamin D deficiency at disease onset exhibited strong association with three SNPs of IL7R; rs987107 (P-value=0.047), rs3194051 (P-value=0.03,) and rs1494571 (P-value=0.036). |
| Mechanism/Pathway | N/A |
