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Basic information of CNR2 :

Official Symbol of Gene CNR2
Species Homo sapiens
Entrez Gene ID 1269
Official Full Name cannabinoid receptor 2
Also known as CB2; CX5; CB-2
Gene Type protein coding
dbXrefs Ensembl:ENSG00000188822 MIM:605051; AllianceGenome:HGNC:2160
Map Location 1p36.11
Variation Type SNP
refSNP ID rs35761398

Sample information of multiple sclerosis:

Detected Sample Blood
Sample Detail N/A
Detected Method PCR,TaqMan
Disease MS
Disease subtype N/A
Population Iranian
Sample Size 100 patients,100 healthy individuals

Literature information of multiple sclerosis :

Pubmed ID 31407233
Year 2020
Title Cannabinoid CB2 Receptor Functional Variation (Q63R) Is Associated with Multiple Sclerosis in Iranian Subjects

Results of multiple sclerosis :

Risk Type Disease risk
Main Result positive
Result The co-dominant, dominant, recessive, over-dominant, and additive inheritance models were analyzed using SNPStats software. A significant genetic association was observed between Q63R polymorphism and MS. The dominant model was accepted as the best inheritance model to fit the data (OR 2.70, 95% CI 1.47-4.97, p = 0.001).
Mechanism/Pathway N/A