Basic information of CXCR5 :
| Official Symbol of Gene | CXCR5 |
| Species | Homo sapiens |
| Entrez Gene ID | 643 |
| Official Full Name | C-X-C motif chemokine receptor 5 |
| Also known as | BLR1; CD185; MDR15 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000160683 MIM:601613; AllianceGenome:HGNC:1060 |
| Map Location | 11q23.3 |
| Variation Type | SNP |
| refSNP ID | rs3922 |
Sample information of multiple sclerosis:
| Detected Sample | Blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | central coastal area of China |
| Sample Size | 263 MS patients from the Han nationality and 138 MS patients from the Hui nationality, 440 healthy volunteers |
Literature information of multiple sclerosis :
| Pubmed ID | 30352019 |
| Year | 2018 |
| Title | A genetic link between CXCR5 and IL2RA gene polymorphisms and susceptibility to multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | N/A |
| Main Result | negative |
| Result | In this study, our findings showed that the occurrence and development of MS had no significant relationship with CXCR5 rs3922. |
| Mechanism/Pathway | Therefore, we speculate thatCXCR5 SNPs may affect its expression, thereby influencing the immune signals it participates in and thus affecting the occurrence and development of MS. |
