Basic information of FTO :
| Official Symbol of Gene | FTO |
| Species | Homo sapiens |
| Entrez Gene ID | 79068 |
| Official Full Name | FTO alpha-ketoglutarate dependent dioxygenase |
| Also known as | GDFD; ALKBH9; BMIQ14 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000140718 MIM:610966; AllianceGenome:HGNC:24678 |
| Map Location | 16q12.2 |
| Variation Type | SNP |
| refSNP ID | rs9939609 |
Sample information of multiple sclerosis:
| Detected Sample | Blood |
| Sample Detail | N/A |
| Detected Method | PCR,TaqMan |
| Disease | MS |
| Disease subtype | N/A |
| Population | South Africa |
| Sample Size | 114 MS, 195 control |
Literature information of multiple sclerosis :
| Pubmed ID | 24532085 |
| Year | 2014 |
| Title | The fat mass and obesity-associated FTO rs9939609 polymorphism is associated with elevated homocysteine levels in patients with multiple sclerosis screened for vascular risk factors |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | positive |
| Result | After adjustment for potential confounders, the risk-associated FTO rs9939609 A-allele was associated with raised homocysteine levels (p = 0.003) in patients diagnosed with MS, but not in controls. |
| Mechanism/Pathway | N/A |
