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Basic information of IL18 :

Official Symbol of Gene IL18
Species Homo sapiens
Entrez Gene ID 3606
Official Full Name interleukin 18
Also known as IGIF; IL-18; IL-1g; IL1F4
Gene Type protein coding
dbXrefs Ensembl:ENSG00000150782 MIM:600953; AllianceGenome:HGNC:5986
Map Location 11q23.1
Variation Type SNP
refSNP ID rs187238

Sample information of multiple sclerosis:

Detected Sample Blood
Sample Detail N/A
Detected Method N/A
Disease MS
Disease subtype RRMS
Population N/A
Sample Size 149 patients

Literature information of multiple sclerosis :

Pubmed ID 24300807
Year 2013
Title [Clinical and electrophysiological and molecular genetic characteristics of the course of relapsing-remitting multiple sclerosis]

Results of multiple sclerosis :

Risk Type Disease risk
Main Result positive
Result Genotype C/C polymorphism rs187238 locus IL-18 gene associated with frequent exacerbations of relapsing-remitting multiple sclerosis, high speed of progression of the disease and is characterized by marked changes in latency of peak V ABR and VEP P100.
Mechanism/Pathway N/A