Basic information of HLA-DRB1 :
| Official Symbol of Gene | HLA-DRB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3123 |
| Official Full Name | major histocompatibility complex, class II, DR beta 1 |
| Also known as | SS1; DRB1; HLA-DRB; HLA-DR1B |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948 |
| Map Location | 6p21.32 |
| Variation Type | SNP |
| refSNP ID | rs3135388 |
Sample information of multiple sclerosis:
| Detected Sample | Blood |
| Sample Detail | N/A |
| Detected Method | PCR,TaqMan |
| Disease | MS |
| Disease subtype | RRMS,SPMS,PRMS |
| Population | Serbia |
| Sample Size | Two hundred sixty nine consecutive patients |
Literature information of multiple sclerosis :
| Pubmed ID | 19433080 |
| Year | 2009 |
| Title | The tag SNP for HLA-DRB1*1501, rs3135388, is significantly associated with multiple sclerosis susceptibility: cost-effective high-throughput detection by real-time PCR |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | positive |
| Result | We found significantly higher frequency of rs3135388 A allele carriers in MS patients compared to controls. |
| Mechanism/Pathway | N/A |
