Basic information of CD6 :
| Official Symbol of Gene | CD6 |
| Species | Homo sapiens |
| Entrez Gene ID | 923 |
| Official Full Name | CD6 molecule |
| Also known as | TP120 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000013725 MIM:186720; AllianceGenome:HGNC:1691 |
| Map Location | 11q12.2 |
| Variation Type | SNP |
| refSNP ID | rs11230563 |
Sample information of multiple sclerosis:
| Detected Sample | Blood |
| Sample Detail | N/A |
| Detected Method | Taq polymerase,PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | African American |
| Sample Size | 918 MS cases, and 656 unrelated control individuals |
Literature information of multiple sclerosis :
| Pubmed ID | 19865102 |
| Year | 2010 |
| Title | Multiple sclerosis susceptibility alleles in African Americans |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | positive |
| Result | CD6, CLEC16a, EVI5, GPC5, and TYK2 contained SNPs that are associated with MS risk in the African American data set. |
| Mechanism/Pathway | Allelic variants at rs11230563 may result in altered activation of T cells, thereby affecting an individual’s susceptibility to MS. |
