Basic information of EVI5 :
| Official Symbol of Gene | EVI5 |
| Species | Homo sapiens |
| Entrez Gene ID | 7813 |
| Official Full Name | ecotropic viral integration site 5 |
| Also known as | NB4S; EVI-5 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000067208 MIM:602942; AllianceGenome:HGNC:3501 |
| Map Location | 1p22.1 |
| Variation Type | SNP |
| refSNP ID | rs6680578 |
Sample information of multiple sclerosis:
| Detected Sample | Blood |
| Sample Detail | N/A |
| Detected Method | Taq polymerase,PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | African American |
| Sample Size | 918 MS cases, and 656 unrelated control individuals |
Literature information of multiple sclerosis :
| Pubmed ID | 19865102 |
| Year | 2010 |
| Title | Multiple sclerosis susceptibility alleles in African Americans |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | positive |
| Result | CD6, CLEC16a, EVI5, GPC5, and TYK2 contained SNPs that are associated with MS risk in the African American data set. |
| Mechanism/Pathway | Allelic differences in EVI5 may contribute to altered function of RAB11 and altered formation of the immunological synapse, thus contributing to MS susceptibility. |
