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Basic information of GPC5 :

Official Symbol of Gene GPC5
Species Homo sapiens
Entrez Gene ID 2262
Official Full Name glypican 5
Also known as N/A
Gene Type protein coding
dbXrefs Ensembl:ENSG00000179399 MIM:602446; AllianceGenome:HGNC:4453
Map Location 13q31.3
Variation Type SNP
refSNP ID rs553717

Sample information of multiple sclerosis:

Detected Sample Blood
Sample Detail N/A
Detected Method Taq polymerase,PCR
Disease MS
Disease subtype N/A
Population African American
Sample Size 918 MS cases, and 656 unrelated control individuals

Literature information of multiple sclerosis :

Pubmed ID 19865102
Year 2010
Title Multiple sclerosis susceptibility alleles in African Americans

Results of multiple sclerosis :

Risk Type Disease risk
Main Result positive
Result CD6, CLEC16a, EVI5, GPC5, and TYK2 contained SNPs that are associated with MS risk in the African American data set.
Mechanism/Pathway Allelic variants of GPC5 may affect neuronal repair and contribute to differences in MS susceptibility.