Basic information of CCL2 :
| Official Symbol of Gene | CCL2 |
| Species | Homo sapiens |
| Entrez Gene ID | 6347 |
| Official Full Name | C-C motif chemokine ligand 2 |
| Also known as | HC11; MCAF; MCP1; MCP-1; SCYA2; GDCF-2; SMC-CF; HSMCR30 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000108691 MIM:158105; AllianceGenome:HGNC:10618 |
| Map Location | 17q12 |
| Variation Type | SNP |
| refSNP ID | rs3917887 |
Sample information of multiple sclerosis:
| Detected Sample | Peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | Inflammatory demyelinating disease (IDD) |
| Disease subtype | multiple sclerosis (MS) and neuromyelitis optica (NMO) |
| Population | Asian |
| Sample Size | 178 IDD patients and 237 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 24786287 |
| Year | 2014 |
| Title | No association between CCL2 gene polymorphisms and risk of inflammatory demyelinating diseases in a Korean population |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | we did not find any association, which was consistent with other studies in Caucasian populations. In conclusion, our results suggest that CCL2 variants may not contribute to the pathogenesis of IDD |
| Result | N/A |
| Mechanism/Pathway | five polymorphisms (rs1024611, rs2857656, rs3917887, rs4586, and rs13900) in this study were presented in the absolute LD, because we have not considered the normalized SNP selection process using various genome databases |
