Basic information of PDGFA :

Official Symbol of Gene	PDGFA
Species	Homo sapiens
Entrez Gene ID	5154
Official Full Name	platelet derived growth factor subunit A
Also known as	PDGF1; PDGF-A
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000197461 MIM:173430; AllianceGenome:HGNC:8799
Map Location	7p22.3
Variation Type	gene polymorphisms
refSNP ID	N/A

Sample information of multiple sclerosis:

Detected Sample	Peripheral blood
Sample Detail	N/A
Detected Method	PCR
Disease	MS
Disease subtype	N/A
Population	French
Sample Size	To test 23 genes coding for growth factors and their receptors as candidates for MS genetic susceptibility in 84 multiplex families of French origin by linkage analysis

Literature information of multiple sclerosis :

Pubmed ID	9748021
Year	1998
Title	A systematic study of oligodendrocyte growth factors as candidates for genetic susceptibility to MS

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	TGFP3, the only gene highlighted by this study, deserves further analysis
Result	The lower limits of the relative risk (Xs) possibly excluded for any candidate gene ranged from 1.3 to 2.8. Positive MLS values (up to 0.93) were observed for transforming growth factor beta 3 (TGFP3) in HLA DR15-associated families, suggesting a possible role for this growth factor in interaction with HLA. Conclusions: Oligodendrocyte growth factors do not play a significant role in MS genetic susceptibility, at least in the tested sample
Mechanism/Pathway	kage of MS to human leukocyte antigen (HLA) DR15