Basic information of CD4 :
| Official Symbol of Gene | CD4 |
| Species | Homo sapiens |
| Entrez Gene ID | 920 |
| Official Full Name | CD4 molecule |
| Also known as | T4; IMD79; Leu-3; OKT4D; CD4mut |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000010610 MIM:186940; AllianceGenome:HGNC:1678 |
| Map Location | 12p13.31 |
| Variation Type | SNP |
| refSNP ID | rs7957426 |
Sample information of multiple sclerosis:
| Detected Sample | Peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Swedish |
| Sample Size | 920 Swedish MS patients |
Literature information of multiple sclerosis :
| Pubmed ID | 17020785 |
| Year | 2006 |
| Title | Association analysis of the LAG3 and CD4 genes in multiple sclerosis in two independent populations |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Three SNPs (rs3782736, rs7957426, rs10774450) showed association at the 5% significance level |
| Result | The result, including a total of 2640 MS patients and 2194 controls shows no significant association with CD4 and LAG3 and MS. We conclude that these genes are of minor importance in regard of genetic predisposition to the MS |
| Mechanism/Pathway | We have investigated the genetic involvement of the CD4 and the LAG3 genes, two appealing candidates for MS due to their suggested role in MS pathology |
