Basic information of CCL14 :
| Official Symbol of Gene | CCL14 |
| Species | Homo sapiens |
| Entrez Gene ID | 6358 |
| Official Full Name | C-C motif chemokine ligand 14 |
| Also known as | CC-1; CC-3; CKB1; MCIF; NCC2; SY14; HCC-1; HCC-3; NCC-2; SCYL2; SCYA14; HCC-1(1-74); HCC-1/HCC-3 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000276409 MIM:601392; AllianceGenome:HGNC:10612 |
| Map Location | 17q12 |
| Variation Type | SNP |
| refSNP ID | rs854680 |
Sample information of multiple sclerosis:
| Detected Sample | DNA, blood or frozen brain tissue specimens |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | N/A |
Literature information of multiple sclerosis :
| Pubmed ID | 18602166 |
| Year | 2008 |
| Title | CCL genes in multiple sclerosis and systemic lupus erythematosus |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | this study reveals strong associations with a marker and a haplotype encompassing the CCL14 gene, which suggests that a lupus relevant variant may lie within or in the proximity of this haplotype |
| Result | After correction for multiple testing, only PG28 (rs854680) remains significant in the SLE group |
| Mechanism/Pathway | This follow up study aims to refine the roles of previously suggested candidate genes (CC chemokine ligands or CCLs) in multiple sclerosis (MS), and to test these markers in another autoimmune disorder, systemic lupus erythematosus (SLE) |
