Basic information of IL18R1 :
| Official Symbol of Gene | IL18R1 |
| Species | Homo sapiens |
| Entrez Gene ID | 8809 |
| Official Full Name | interleukin 18 receptor 1 |
| Also known as | CD218a; IL18RA; IL1RRP; CDw218a; IL-1Rrp; IL-18Ralpha; IL18Ralpha2; IL-18R-alpha |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000115604 MIM:604494; AllianceGenome:HGNC:5988 |
| Map Location | 2q12.1 |
| Variation Type | SNP |
| refSNP ID | rs3213733 |
Sample information of multiple sclerosis:
| Detected Sample | CSF |
| Sample Detail | N/A |
| Detected Method | Quantitative real-time PCR |
| Disease | MS |
| Disease subtype | RRMSã€PPMSã€SPMS |
| Population | N/A |
| Sample Size | 2153 MS patients and 1733 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 20354066 |
| Year | 2010 |
| Title | Interleukin 18 Receptor 1 expression distinguishes patients with multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | The absence of a genetic association in the IL18R1 gene itself suggests regulation from other parts of the genome, or as part of the inflammatory cascade in multiple sclerosis without a prime genetic cause. |
| Result | using 13 tagging single nucleotide polymorphisms (SNPs) across the IL18R1 gene, but determined no SNP or haplotype association |
| Mechanism/Pathway | The interleukin 18 receptor 1 (IL18R1) was recently identified to regulate experimental autoimmune |
