Basic information of SLC11A1 :
| Official Symbol of Gene | SLC11A1 |
| Species | Homo sapiens |
| Entrez Gene ID | 6556 |
| Official Full Name | solute carrier family 11 member 1 |
| Also known as | LSH; NRAMP; NRAMP1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000018280 MIM:600266; AllianceGenome:HGNC:10907 |
| Map Location | 2q35 |
| Variation Type | allele |
| refSNP ID | 5 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | South African Caucasian |
| Sample Size | 104 patients diagnosed with MS and 522 Caucasian controls |
Literature information of multiple sclerosis :
| Pubmed ID | 11358358 |
| Year | 2001 |
| Title | Analysis of the NRAMP1 gene implicated in iron transport: association with multiple sclerosis and age effects |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | Comparison of Allelic Distribution between South African MS Patients (22 Males, 82 Females) and Controls |
| Mechanism/Pathway | The many cellular functions dependent on iron and other metal ions as cofactors may explain the complex role of NRAMP1 in infectious and autoimmune disease. |
