Basic information of VAMP2 :

Official Symbol of Gene	VAMP2
Species	Homo sapiens
Entrez Gene ID	6844
Official Full Name	vesicle associated membrane protein 2
Also known as	SYB2; VAMP-2; NEDHAHM
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000220205 MIM:185881; AllianceGenome:HGNC:12643
Map Location	17p13.1
Variation Type	polymorphisms
refSNP ID	N/A

Sample information of multiple sclerosis:

Detected Sample	Peripheral blood
Sample Detail	N/A
Detected Method	PCR
Disease	MS
Disease subtype	N/A
Population	N/A
Sample Size	87 patients with relapsing-remitting multiple sclerosis, 32 patients with secondary progressive multiple sclerosis, 4 patients with primary progressive multiple sclerosis, and 123 patients with MS were enrolled in this study

Literature information of multiple sclerosis :

Pubmed ID	30941131
Year	2019
Title	The Association Between Vitamin D and Multiple Sclerosis Risk: 1,25(OH)2D3 Induces Super-Enhancers Bound by VDR

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	It is the first time that VSEs have been analyzed, and we directly connect the genetic risk factors for MS risk with Vitamin D based on VSEs.
Result	we reanalyse public ChIP-seq and RNA-seq data to classify VSEs into three categories according to their combinations of persistent and secondary VDR binding. Secondly, we indicate the genes with VSE regions that are near MS risk variants. Furthermore, we find that MS risk variants are enriched in VSE regions, and we indicate some genes with a VSE overlapping MS risk variant for further exploration. We also find two clusters of genes from the set of genes showing correlation of expression patterns with the MS risk gene ZMIZ1 that appear to be regulated by VSEs in THP-1 cell
Mechanism/Pathway	transcription factor (TF) binding regions