Basic information of MBP :
| Official Symbol of Gene | MBP |
| Species | Homo sapiens |
| Entrez Gene ID | 4155 |
| Official Full Name | myelin basic protein |
| Also known as | N/A |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000197971 MIM:159430; AllianceGenome:HGNC:6925 |
| Map Location | 18q23 |
| Variation Type | allele |
| refSNP ID | 1.29 kb |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | peripheral blood |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | italian |
| Sample Size | 54 sporadic patients, 55 control subjects and 18 families with two or more affected individuals |
Literature information of multiple sclerosis :
| Pubmed ID | 7530769 |
| Year | 1994 |
| Title | The myelin basic protein gene is not a major susceptibility locus for multiple sclerosis in Italian patients |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | Our data indicate that in the Italian population the myelin basic protein gene does not play a major role in conferring genetic susceptibility to multiple sclerosis. |
| Mechanism/Pathway | a significant association between MS and a multiallelic polymorphism identified upstream from the 5" end of the human MBP gene on chromosome 18. |
