Basic information of PRKCA :
| Official Symbol of Gene | PRKCA |
| Species | Homo sapiens |
| Entrez Gene ID | 5578 |
| Official Full Name | protein kinase C alpha |
| Also known as | AAG6; PKCA; PRKACA; PKCI+/-; PKCalpha; PKC-alpha |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000154229 MIM:176960; AllianceGenome:HGNC:9393 |
| Map Location | 17q24.2 |
| Variation Type | SNP |
| refSNP ID | rs7220007 |
Sample information of multiple sclerosis:
| Detected Sample | brain |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | 211 Finnish and 554 Canadian MS families |
Literature information of multiple sclerosis :
| Pubmed ID | 16596167 |
| Year | 2006 |
| Title | PRKCA and Multiple Sclerosis: Association in Two Independent Populations |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | positive |
| Result | The transcript levels of PRKCA showed correlation with the copy number of the Finnish and Canadian ‘‘risk’’ haplotypes in CD4-negative mononuclear cells of five Finnish multiplex families and in lymphoblast cell lines of 11 Centre d’Etude du Polymorphisme Humain (CEPH) individuals of European origin |
| Mechanism/Pathway | PKC |
