Basic information of ERG :
| Official Symbol of Gene | ERG |
| Species | Homo sapiens |
| Entrez Gene ID | 2078 |
| Official Full Name | ETS transcription factor ERG |
| Also known as | p55; erg-3 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000157554 MIM:165080; AllianceGenome:HGNC:3446 |
| Map Location | 21q22.2 |
| Variation Type | DNA methylation |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMSã€SPMS |
| Population | Japanese |
| Sample Size | 79 unrelated Japanese |
Literature information of multiple sclerosis :
| Pubmed ID | 11054488 |
| Year | 2000 |
| Title | Estrogen receptor gene polymorphism in Japanese patients with multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | positive |
| Result | ERG polymorphism should whereas in the late-stage pregnancy group, no difference in be further studied in other populations to obtain more BMD was shown in XbaI polymorphism. The Xx genotype adequate strategies for treatment of MS. |
| Mechanism/Pathway | After informed consent was obtained from each subject, and human leukocyte antigens (HLA). high-molecular weight DNA was extracted from their peripheral blood cells. Polymerase chain reaction (PCR) amplification was performed on the region containing the PvuII and XbaI polymorphisms |
