Basic information of HLA-DRB1 :

Official Symbol of Gene	HLA-DRB1
Species	Homo sapiens
Entrez Gene ID	3123
Official Full Name	major histocompatibility complex, class II, DR beta 1
Also known as	SS1; DRB1; HLA-DRB; HLA-DR1B
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948
Map Location	6p21.32
Variation Type	restriction fragment length polymorphism
refSNP ID	N/A

Sample information of multiple sclerosis:

Detected Sample	peripheral blood
Sample Detail	N/A
Detected Method	PCR
Disease	MS
Disease subtype	N/A
Population	northeast Scotland
Sample Size	50 patients and 76 healthy unrelated controls

Literature information of multiple sclerosis :

Pubmed ID	2567726
Year	1989
Title	An Allelic Cluster of DQa Restriction Fragments Is Associated with Multiple Sclerosis: Evidence That a Second Haplotype May Influence Disease Susceptibility

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	positive
Result	Pooled DNA from Scottish DR2-positive individuals digested with Mspl and probed with HLADQc~, showing the presence of a 3.25-kb fragment in MS patients (A) but not in healthy unrelated controls (B)
Mechanism/Pathway	The use of DNA pooled from groups of patients and controls from northeast Scotland enabled the screening of 14 restriction endonucleases with five HLA-D region probes (DPa, DPB, DQa, DQRB) and two T-cell antigen receptor probes