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Basic information of HLA-DPA1 :

Official Symbol of Gene HLA-DPA1
Species Homo sapiens
Entrez Gene ID 3113
Official Full Name major histocompatibility complex, class II, DP alpha 1
Also known as DPA1; PLT1; HLADP; HLASB; DP(W3); DP(W4); HLA-DPA; HLA-DP1A; HLA-DPB1
Gene Type protein coding
dbXrefs Ensembl:ENSG00000231389 MIM:142880; AllianceGenome:HGNC:4938
Map Location 6p21.32
Variation Type restriction fragment length polymorphism
refSNP ID N/A

Sample information of multiple sclerosis:

Detected Sample peripheral blood
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype N/A
Population northeast Scotland
Sample Size 50 patients and 76 healthy unrelated controls

Literature information of multiple sclerosis :

Pubmed ID 2567726
Year 1989
Title An Allelic Cluster of DQa Restriction Fragments Is Associated with Multiple Sclerosis: Evidence That a Second Haplotype May Influence Disease Susceptibility

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Negative
Result No polymorphism discriminating between MS and control pools was seen using DRB, DPa, DPB, TcRa, orTcRB geneprobes
Mechanism/Pathway The use of DNA pooled from groups of patients and controls from northeast Scotland enabled the screening of 14 restriction endonucleases with five HLA-D region probes (DPa, DPB, DQa, DQRB) and two T-cell antigen receptor probes