Home Details
| Official Symbol of Gene | HLA-DPA1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3113 |
| Official Full Name | major histocompatibility complex, class II, DP alpha 1 |
| Also known as | DPA1; PLT1; HLADP; HLASB; DP(W3); DP(W4); HLA-DPA; HLA-DP1A; HLA-DPB1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000231389 MIM:142880; AllianceGenome:HGNC:4938 |
| Map Location | 6p21.32 |
| Variation Type | restriction fragment length polymorphism |
| refSNP ID | N/A |
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | northeast Scotland |
| Sample Size | 50 patients and 76 healthy unrelated controls |
| Pubmed ID | 2567726 |
| Year | 1989 |
| Title | An Allelic Cluster of DQa Restriction Fragments Is Associated with Multiple Sclerosis: Evidence That a Second Haplotype May Influence Disease Susceptibility |
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | No polymorphism discriminating between MS and control pools was seen using DRB, DPa, DPB, TcRa, orTcRB geneprobes |
| Mechanism/Pathway | The use of DNA pooled from groups of patients and controls from northeast Scotland enabled the screening of 14 restriction endonucleases with five HLA-D region probes (DPa, DPB, DQa, DQRB) and two T-cell antigen receptor probes |

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