Home Details
| Official Symbol of Gene | HLA-DPB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3115 |
| Official Full Name | major histocompatibility complex, class II, DP beta 1 |
| Also known as | DPB1; HLA-DP; HLA-DPB; HLA-DP1B |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000223865 MIM:142858; AllianceGenome:HGNC:4940 |
| Map Location | 6p21.32 |
| Variation Type | restriction fragment length polymorphism |
| refSNP ID | N/A |
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | northeast Scotland |
| Sample Size | 50 patients and 76 healthy unrelated controls |
| Pubmed ID | 2567726 |
| Year | 1989 |
| Title | An Allelic Cluster of DQa Restriction Fragments Is Associated with Multiple Sclerosis: Evidence That a Second Haplotype May Influence Disease Susceptibility |
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | No polymorphism discriminating between MS and control pools was seen using DRB, DPa, DPB, TcRa, orTcRB geneprobes |
| Mechanism/Pathway | The use of DNA pooled from groups of patients and controls from northeast Scotland enabled the screening of 14 restriction endonucleases with five HLA-D region probes (DPa, DPB, DQa, DQRB) and two T-cell antigen receptor probes |

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