Basic information of HLA-DPB1 :

Official Symbol of Gene	HLA-DPB1
Species	Homo sapiens
Entrez Gene ID	3115
Official Full Name	major histocompatibility complex, class II, DP beta 1
Also known as	DPB1; HLA-DP; HLA-DPB; HLA-DP1B
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000223865 MIM:142858; AllianceGenome:HGNC:4940
Map Location	6p21.32
Variation Type	restriction fragment length polymorphism
refSNP ID	N/A

Sample information of multiple sclerosis:

Detected Sample	peripheral blood
Sample Detail	N/A
Detected Method	PCR
Disease	MS
Disease subtype	N/A
Population	Northern Ireland
Sample Size	patients consisted of 51 unrelated MS patients

Literature information of multiple sclerosis :

Pubmed ID	1420118
Year	1992
Title	FREQUENCY OF HLA-DPB1 ALLELES IN MULTIPLE SCLEROSIS PATIENTS FROM NORTHERN IRELAND

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	Negative
Result	Using sequence-specific oligonucleotide probes, no altered distribution in the frequency of HLA-DPB1 alleles was found in multiple sclerosis patients from Northern Ireland. Although present in the controls, linkage disequilibrium between HLA-DPBl*OlOl and HLA-DR17 was not found in multiple sclerosis patients.
Mechanism/Pathway	We have extended our previous study by oligonucleotide typing the same group of patients for HLA-DPB1 alleles and comparing the frequency of these alleles with controls from the same population.