Basic information of AGER :

Official Symbol of Gene	AGER
Species	Homo sapiens
Entrez Gene ID	177
Official Full Name	advanced glycosylation end-product specific receptor
Also known as	RAGE; sRAGE; SCARJ1
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000204305 MIM:600214; AllianceGenome:HGNC:320
Map Location	6p21.32
Variation Type	genotype
refSNP ID	374 T/A

Sample information of multiple sclerosis:

Detected Sample	blood
Sample Detail	peripheral blood
Detected Method	PCR
Disease	MS
Disease subtype	RRMS, SPMS
Population	N/A
Sample Size	168 patients with MS were enrolled; 136 healthy blood donors served as controls

Literature information of multiple sclerosis :

Pubmed ID	19757202
Year	2009
Title	RAGE gene polymorphisms in patients with multiple sclerosis

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	Positive
Result	There was a significant difference in RAGE 374 T/A genotype distribution between the controls and the MS patients.
Mechanism/Pathway	The receptor for advanced glycation end products (RAGE) is a member of immunoglobulin superfamily of cell surface molecules.