Basic information of APOE :
| Official Symbol of Gene | APOE |
| Species | Homo sapiens |
| Entrez Gene ID | 348 |
| Official Full Name | apolipoprotein E |
| Also known as | AD2; LPG; APO-E; ApoE4; LDLCQ5 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000130203 MIM:107741; AllianceGenome:HGNC:613 |
| Map Location | 19q13.32 |
| Variation Type | genotype |
| refSNP ID | rs405509 [ 219 G/G] |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | SPMS, RRMS |
| Population | Australian |
| Sample Size | 1,006 patients |
Literature information of multiple sclerosis :
| Pubmed ID | 19786693 |
| Year | 2009 |
| Title | Apolipoprotein genotype does not influence MS severity, cognition, or brain atrophy |
Results of multiple sclerosis :
| Risk Type | Phenotype risk |
| Main Result | Negative |
| Result | In this MS study, neither APOE allele status nor promoter region heterogeneity at positions β219 G/T or 113 C/G influenced the clinical disease severity, cognition, or cerebral atrophy. |
| Mechanism/Pathway | N/A |
