Basic information of MMP3 :
| Official Symbol of Gene | MMP3 |
| Species | Homo sapiens |
| Entrez Gene ID | 4314 |
| Official Full Name | matrix metallopeptidase 3 |
| Also known as | SL-1; STMY; STR1; CHDS6; MMP-3; STMY1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000149968 MIM:185250; AllianceGenome:HGNC:7173 |
| Map Location | 11q22.2 |
| Variation Type | polymorphisms |
| refSNP ID | 5A/6A |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | peripheral blood cells |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMS, SPMS |
| Population | Serbia |
| Sample Size | 184 MS patients (150 RR, 34 SP) and 236 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 17942123 |
| Year | 2008 |
| Title | Association of the MMP-3 5A/6A gene polymorphism with multiple sclerosis in patients from Serbia |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | Results show that the distribution of MMP-3 5A/6A genotype frequencies between MS patients and controls were not significantly different. |
| Mechanism/Pathway | MMP-3 cleaves human myelin basic protein (MBP). |
