Basic information of LINE-1 :
| Official Symbol of Gene | LINE-1 |
| Species | Homo sapiens |
| Entrez Gene ID | 54596 |
| Official Full Name | LINE1 type transposase domain containing 1 |
| Also known as | ECAT11 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000240563 AllianceGenome:HGNC:25595 |
| Map Location | 1p31.3 |
| Variation Type | methylation |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | serum |
| Detected Method | Quantitative PCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | N/A |
| Sample Size | 12 MS patients and 12 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 28707075 |
| Year | 2018 |
| Title | LINE-1 Hypermethylation in Serum Cell-Free DNA of Relapsing Remitting Multiple Sclerosis Patients |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result |
The methylation level of L1PA2 CpG site 10 was significantly and negatively correlated with the EDSS score (the correlation coefficient is |
| Mechanism/Pathway | N/A |
