Basic information of APOE :
| Official Symbol of Gene | APOE |
| Species | Homo sapiens |
| Entrez Gene ID | 348 |
| Official Full Name | apolipoprotein E |
| Also known as | AD2; LPG; APO-E; ApoE4; LDLCQ5 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000171791 MIM:151430; AllianceGenome:HGNC:990 |
| Map Location | 19q13.32 |
| Variation Type | genotype |
| refSNP ID | E2/E2 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMS, SPMS, PPMS |
| Population | N/A |
| Sample Size | patients and healthy volunteers were collected (n = 40) |
Literature information of multiple sclerosis :
| Pubmed ID | 22973358 |
| Year | 2011 |
| Title | Polymorphism of Apo lipoprotein E gene and the risk of multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | We found no significant differences in genotype frequency between patients with multiple sclerosis and the control group. |
| Mechanism/Pathway | Apolipoprotein E (ApoE) gene encodes an important protein in reforming injuries of central nervous system (CNS). |
