Details

Home Details


Basic information of HLA-DRB1 :

Official Symbol of Gene HLA-DRB1
Species Homo sapiens
Entrez Gene ID 3123
Official Full Name major histocompatibility complex, class II, DR beta 1
Also known as SS1; DRB1; HLA-DRB; HLA-DR1B
Gene Type protein coding
dbXrefs Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948
Map Location 6p21.32
Variation Type allele
refSNP ID DR4

Sample information of multiple sclerosis:

Detected Sample blood
Sample Detail venous blood
Detected Method PCR
Disease MS
Disease subtype N/A
Population Norwegian
Sample Size MS(n = 608), control(n = 558)

Literature information of multiple sclerosis :

Pubmed ID 14989713
Year 2004
Title Genes in the HLA class I region may contribute to the HLA class II-associated genetic susceptibility to multiple sclerosis

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Positive
Result HLA-DR, HLA-B, and HLA-A allele frequencies in Norwegian multiple sclerosis (MS) cases and controls
Mechanism/Pathway N/A