Basic information of NFKB1 :
| Official Symbol of Gene | NFKB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 4790 |
| Official Full Name | nuclear factor kappa B subunit 1 |
| Also known as | KBF1; EBP-1; NF-kB; CVID12; NF-kB1; NFKB-p50; NFkappaB; NF-kappaB; NFKB-p105; NF-kappa-B1; NF-kappabeta |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000109320 MIM:164011; AllianceGenome:HGNC:7794 |
| Map Location | 4q24 |
| Variation Type | SNP |
| refSNP ID | rs7665090 |
Sample information of multiple sclerosis:
| Detected Sample | N/A |
| Sample Detail | N/A |
| Detected Method | N/A |
| Disease | N/A |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | 490 paediatric-onset multiple sclerosis cases and 716 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 36725329 |
| Year | 2023 |
| Title | Gene-environment interactions increase the risk of paediatric-onset multiple sclerosis associated with household chemical exposures |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | There was significant additive interaction between exposure to weed control products and NFKB1 SNP GG (attributable proportions (AP) 0.48, 95% CI 0.10 to 0.87), and exposure to plant or disease control products and absence of HLA-A*02 (AP 0.56; 95% CI 0.03 to 1.08). |
| Mechanism/Pathway | N/A |
