Basic information of TRB :
| Official Symbol of Gene | TRB |
| Species | Homo sapiens |
| Entrez Gene ID | 6957 |
| Official Full Name | T cell receptor beta locus |
| Also known as | TCRB; TRB@ |
| Gene Type | protein coding |
| dbXrefs | AllianceGenome:HGNC:12155 |
| Map Location | 7q34 |
| Variation Type | rearrangement |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | peripheral blood mononuclear cells |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | N/A |
| Sample Size | N/A |
Literature information of multiple sclerosis :
| Pubmed ID | 9701037 |
| Year | 1998 |
| Title | Restricted TCR Valpha gene rearrangements in T cells recognizing an immunodominant peptide of myelin basic protein in DR2 patients with multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | Interestingly, the DR2-restricted T cell clones displayed a biased V gene usage for Vα3 and Vα8, while Vβ gene rearrangements were highly heterogeneous. |
| Mechanism/Pathway | N/A |
