Basic information of ERVW-1 :

Official Symbol of Gene	ERVW-1
Species	Homo sapiens
Entrez Gene ID	30816
Official Full Name	endogenous retrovirus group W member 1, envelope
Also known as	ENV; ENVW; HERVW; ERVWE1; HERV7Q; HERV-7q; HERVWENV; HERV-W-ENV
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000242950 MIM:604659; AllianceGenome:HGNC:13525
Map Location	7q21.2
Variation Type	DNA copy number
refSNP ID	N/A

Sample information of multiple sclerosis:

Detected Sample	blood
Sample Detail	peripheral blood leukocytes
Detected Method	real-time PCR
Disease	MS
Disease subtype	N/A
Population	N/A
Sample Size	N/A

Literature information of multiple sclerosis :

Pubmed ID	23212585
Year	2012
Title	Molecular characteristics of Human Endogenous Retrovirus type-W in schizophrenia and bipolar disorder

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	Positive
Result	HERV-W env transcription was found to be elevated in BD (Po10–4) and in SZ (P 0.012) as compared with HC, but with higher values in BD than in SZ group (Po0.01).
Mechanism/Pathway	HERV-W envelope gene (env) is activated by environmental factors and encodes a protein displaying inflammation and neurotoxicity.