Basic information of NOS3 :
| Official Symbol of Gene | NOS3 |
| Species | Homo sapiens |
| Entrez Gene ID | 4846 |
| Official Full Name | nitric oxide synthase 3 |
| Also known as | eNOS; ECNOS |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000164867 MIM:163729; AllianceGenome:HGNC:7876 |
| Map Location | 7q36.1 |
| Variation Type | SNP |
| refSNP ID | rs2070744 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | venous blood |
| Detected Method | qPCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Caucasian Spanish |
| Sample Size | 300 patients diagnosed with MS and 380 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 32449012 |
| Year | 2020 |
| Title | Endothelial nitric oxide synthase (NOS3) rs2070744 polymorphism and risk for multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | The frequencies of rs2070744 genotypes and allelic variants were not associated with the risk of developing MS and were not infuenced by gender, age at onset and severity of MS, the clinical subtype of MS or the HLA-DRB1*1501 genotype. |
| Mechanism/Pathway | N/A |
