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Basic information of MT-TT :

Official Symbol of Gene MT-TT
Species Homo sapiens
Entrez Gene ID 4576
Official Full Name mitochondrially encoded tRNA threonine
Also known as MTTT; TRNT
Gene Type tRNA
dbXrefs MIM:590090; AllianceGenome:HGNC:7499
Map Location N/A
Variation Type variation
refSNP ID G15257A

Sample information of multiple sclerosis:

Detected Sample blood
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype N/A
Population Iranian
Sample Size 100 MS patients and 100 unrelated healthy controls

Literature information of multiple sclerosis :

Pubmed ID 26233806
Year 2015
Title Lack of association between mitochondrial DNA G15257A and G15812A variations and multiple sclerosis

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Positive
Result The mtDNA G15257A variation was found in one of the 100 patients and one of the 100 controls.
Mechanism/Pathway Mitochondrial DNA (mtDNA) is more vulnerable to damage and mutation than nuclear DNA, due to the highly oxidizing environment of the mitochondria.