Basic information of HLA-DQA1 :
| Official Symbol of Gene | HLA-DQA1 |
| Species | Homo sapiens (human) |
| Entrez Gene ID | 3117 |
| Official Full Name | major histocompatibility complex, class II, DQ alpha 1 |
| Also known as | DQA1; DQ-A1; CELIAC1; HLA-DQA; HLA-DQB1; HLA-DQA1* |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000196735 MIM:146880; AllianceGenome:HGNC:4942 |
| Map Location | 6p21.32 |
| Variation Type | haplotype |
| refSNP ID | DRB5*0101-DQA1*0102-DQB1*0602 |
Sample information of multiple sclerosis:
| Detected Sample | N/A |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Iceland |
| Sample Size | 91 unrelated Iceland MS patients and 91 unrelated controls |
Literature information of multiple sclerosis :
| Pubmed ID | 8780100 |
| Year | 1996 |
| Title | Evidence for a complex role of HLA class II genotypes in susceptibility to multiple sclerosis in Iceland |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | By the RPE method, the DR2 haplotype, DRB5*0101-DQA1*0102 DQB1*0602, was found to be predispositional (Z = 3.54; p < 0.0004) and had a RR = 2.43; 95% confidence interval (CI) for the RR was 1.43 to 4.13. |
| Mechanism/Pathway | N/A |
