Basic information of HLA-DQB1 :
| Official Symbol of Gene | HLA-DQB1 |
| Species | Homo sapiens (human) |
| Entrez Gene ID | 3119 |
| Official Full Name | major histocompatibility complex, class II, DQ beta 1 |
| Also known as | IDDM1; CELIAC1; HLA-DQB |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000179344 MIM:604305; AllianceGenome:HGNC:4944 |
| Map Location | 6p21.32 |
| Variation Type | haplotype |
| refSNP ID | DRB1*1302-DQA1*0102-DQBl*0604 |
Sample information of multiple sclerosis:
| Detected Sample | N/A |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Iceland |
| Sample Size | 91 unrelated Iceland MS patients and 91 unrelated controls |
Literature information of multiple sclerosis :
| Pubmed ID | 8780100 |
| Year | 1996 |
| Title | Evidence for a complex role of HLA class II genotypes in susceptibility to multiple sclerosis in Iceland |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | After removal of this DR2 haplotype from the analysis, a DR13 haplotype (DRB1'~1302-DQA1'''0102-DQBl"0604) was found to be protective (Z = 2.04; p < 0.04) and had a RR = 0.33; 95% CI for the RR was 0.13 to 0.82. |
| Mechanism/Pathway | N/A |
