Basic information of HLA-DRB5 :
| Official Symbol of Gene | HLA-DRB5 |
| Species | Homo sapiens |
| Entrez Gene ID | 3127 |
| Official Full Name | major histocompatibility complex, class II, DR beta 5 |
| Also known as | DRB5; HLA-DRB5* |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000198502 MIM:604776; AllianceGenome:HGNC:4953 |
| Map Location | 6p21.32 |
| Variation Type | polymorphisms |
| refSNP ID | DRB5*0101 |
Sample information of multiple sclerosis:
| Detected Sample | N/A |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Iceland |
| Sample Size | 91 unrelated Iceland MS patients and 91 unrelated controls |
Literature information of multiple sclerosis :
| Pubmed ID | 8780100 |
| Year | 1996 |
| Title | Evidence for a complex role of HLA class II genotypes in susceptibility to multiple sclerosis in Iceland |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | The significant difference obtained with the x2 disequilibrium statisticz3 (x2 = 6.55, p < 0.05) suggests that the DR2 allele and MS cosegregate and that there is linkage. |
| Mechanism/Pathway | N/A |
