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Basic information of Tcrb :

Official Symbol of Gene Tcrb
Species Rattus norvegicus
Entrez Gene ID 24820
Official Full Name T-cell receptor beta chain
Also known as TCB; TCBC1; RATTCB; RATTCBC1
Gene Type protein coding
dbXrefs N/A
Map Location 4q22
Variation Type polymorphisms
refSNP ID Va

Sample information of multiple sclerosis:

Detected Sample N/A
Sample Detail N/A
Detected Method N/A
Disease EAE
Disease subtype N/A
Population Lewis rats
Sample Size N/A

Literature information of multiple sclerosis :

Pubmed ID 1714476
Year 1991
Title Nonencephalitogenic CD4-CD8- V alpha 2V beta 8.2+ anti-myelin basic protein rat T lymphocytes inhibit disease

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Negative
Result Thus, TCR Va2VB8.2 and its junctional region gene products are not the only prerequisite segment for a T cell to become encephalitogenic.
Mechanism/Pathway N/A