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Basic information of CHRNA7 :

Official Symbol of Gene CHRNA7
Species Homo sapiens
Entrez Gene ID 1139
Official Full Name cholinergic receptor nicotinic alpha 7 subunit
Also known as NACHRA7; CHRNA7-2
Gene Type protein coding
dbXrefs Ensembl:ENSG00000175344 MIM:118511; AllianceGenome:HGNC:1960
Map Location 15q13.3
Variation Type SNP
refSNP ID rs11635209

Sample information of multiple sclerosis:

Detected Sample N/A
Sample Detail N/A
Detected Method N/A
Disease MS
Disease subtype N/A
Population N/A
Sample Size 286 cases, 176 controls

Literature information of multiple sclerosis :

Pubmed ID 32924781
Year 2021
Title Nicotinic acetylcholine receptors α7 and α9 modifies tobacco smoke risk for multiple sclerosis

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Positive
Result The results suggest that CHRNA7 and CHRNA9 modifies MS risk conferred by tobacco smoke, where risk among smokers was increased in carriers of the minor CHRNA9 haplotype and in non carriers the minor CHRNA7 haplotype.
Mechanism/Pathway N/A