Basic information of Tcrb :
| Official Symbol of Gene | Tcrb |
| Species | Mus musculus |
| Entrez Gene ID | 21577 |
| Official Full Name | T cell receptor beta chain |
| Also known as | Tib; TCRbeta |
| Gene Type | protein coding |
| dbXrefs | N/A |
| Map Location | 6 B1; 6 |
| Variation Type | polymorphisms |
| refSNP ID | Vβ8.2 |
Sample information of multiple sclerosis:
| Detected Sample | N/A |
| Sample Detail | CD4 T cells |
| Detected Method | PCR |
| Disease | EAE |
| Disease subtype | N/A |
| Population | B10PL mice |
| Sample Size | N/A |
Literature information of multiple sclerosis :
| Pubmed ID | 12824465 |
| Year | 2003 |
| Title | Regulatory CD8+ T cells fine-tune the myelin basic protein-reactive T cell receptor V beta repertoire during experimental autoimmune encephalomyelitis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | In EAE-recovered mice, certain myelin basic protein-reactive CD4βV8.2β clones are significantly decreased and this decrease is not observed if CD8β T cells were depleted from these mice. |
| Mechanism/Pathway | N/A |
