Home Details
| Official Symbol of Gene | CD6 |
| Species | Homo sapiens |
| Entrez Gene ID | 923 |
| Official Full Name | CD6 molecule |
| Also known as | TP120 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000013725 MIM:186720; AllianceGenome:HGNC:1691 |
| Map Location | 11q12.2 |
| Variation Type | SNP |
| refSNP ID | rs11230555 |
| Detected Sample | blood |
| Sample Detail | N/A |
| Detected Method | N/A |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | 2265 MS patients and 2600 healthy controls |
| Pubmed ID | 23638056 |
| Year | 2013 |
| Title | Fine mapping and functional analysis of the multiple sclerosis risk gene CD6 |
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | We identified association of haplotypes composed of two non synonymous SNPs [rs11230563 (R225W) and rs2074225(A257V)] in the 2nd SRCR domain with susceptibility to MS. |
| Mechanism/Pathway | CD6 is a cell surface scavenger receptor involved in T-cell activation and proliferation, as well as in thymocyte differentiation. |

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