Basic information of CYP27B1 :
| Official Symbol of Gene | CYP27B1 |
| Species | Homo sapiens |
| Entrez Gene ID | 1594 |
| Official Full Name | cytochrome P450 family 27 subfamily B member 1 |
| Also known as | VDR; CP2B; CYP1; PDDR; VDD1; VDDR; VDDRI; CYP27B; P450c1; CYP1alpha |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000111012 MIM:609506; AllianceGenome:HGNC:2606 |
| Map Location | 12q14.1 |
| Variation Type | genotype |
| refSNP ID | rs703842 TT |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | serum |
| Detected Method | N/A |
| Disease | MS |
| Disease subtype | RRMS |
| Population | Altai |
| Sample Size | 90 patients with relapsing—remitting MS and 87 volunteers without MS |
Literature information of multiple sclerosis :
| Pubmed ID | 32844632 |
| Year | 2020 |
| Title | [Association between vitamin D status and CYP27b1 and CYP24A1 gene polymorphisms in patients with multiple sclerosis in the Altai region] |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | A relationship between the MS risk and the TC genotype CYP27B1 (rs703842) was identified. |
| Mechanism/Pathway | N/A |
