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Basic information of HLA-DRB1 :

Official Symbol of Gene HLA-DRB1
Species Homo sapiens
Entrez Gene ID 3123
Official Full Name major histocompatibility complex, class II, DR beta 1
Also known as SS1; DRB1; HLA-DRB; HLA-DR1B
Gene Type protein coding
dbXrefs Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948
Map Location 6p21.32
Variation Type polymorphisms
refSNP ID DRW6

Sample information of multiple sclerosis:

Detected Sample blood
Sample Detail N/A
Detected Method N/A
Disease MS
Disease subtype RRMS, PPMS
Population N/A
Sample Size 261 patients and 369 controls

Literature information of multiple sclerosis :

Pubmed ID 6978384
Year 1982
Title HLA profiles in multiple sclerosis suggest two forms of disease and the existence of protective haplotypes

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Positive
Result DR1, DRW6, and DR7 were decreased in MS and DR3 was increased.
Mechanism/Pathway N/A