Basic information of IL7R :
| Official Symbol of Gene | IL7R |
| Species | Homo sapiens |
| Entrez Gene ID | 3575 |
| Official Full Name | interleukin 7 receptor |
| Also known as | ILRA; CD127; IL7RA; CDW127; IMD104; sIL-7R; lnc-IL7R; IL7Ralpha; IL-7Ralpha; IL-7R-alpha |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000168685 MIM:146661; AllianceGenome:HGNC:6024 |
| Map Location | 5p13.2 |
| Variation Type | haplotypes |
| refSNP ID | Hap2 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | Peripheral blood mononucleocytes |
| Detected Method | N/A |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | MS cases and trios |
Literature information of multiple sclerosis :
| Pubmed ID | 20187771 |
| Year | 2010 |
| Title | Interleukin 7 receptor alpha chain haplotypes vary in their influence on multiple sclerosis susceptibility and response to interferon Beta |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | We demonstrate that IL-7Rα is up-regulated in response to IFN β in vitro for haplotypes 1 and 2, but not 4. |
| Mechanism/Pathway | N/A |
