Basic information of LTA :
| Official Symbol of Gene | LTA |
| Species | Homo sapiens |
| Entrez Gene ID | 4049 |
| Official Full Name | lymphotoxin alpha |
| Also known as | LT; TNFB; TNFSF1; TNLG1E |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000226979 MIM:153440; AllianceGenome:HGNC:6709 |
| Map Location | 6p21.33 |
| Variation Type | polymorphisms |
| refSNP ID | TNF-β NcoI |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | Peripheral blood |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMS, SPMS, PPMS |
| Population | N/A |
| Sample Size | 123 female and 43 male patients with MS |
Literature information of multiple sclerosis :
| Pubmed ID | 25173940 |
| Year | 2014 |
| Title | Tumor necrosis factor beta NcoI polymorphism is associated with inflammatory and metabolic markers in multiple sclerosis patients |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The TNFB2/B2 genotype of TNF-β NcoI polymorphism was associated with increased inflammatory and metabolic markers and this association was different according to sex of MS patients. |
| Mechanism/Pathway | N/A |
